Frameshift mutations of Wnt pathway genes AXIN2 and TCF7L2 in gastric carcinomas with high microsatellite instability

A National Cancer Institute Workshop on Microsatellite Instability for cancer detection and familial predisposition: development of international criteria for the determination of microsatellite instability in colorectal cancer.

C. Richard Boland, Stephen N. Thibodeau, Stanley R. Hamilton et al. · PubMed · 1998 · 4.1K citations

Genetic Testing, Cancer Pathology, Genetics +19

Activation of β-Catenin-Tcf Signaling in Colon Cancer by Mutations in β-Catenin or APC

Patrice J. Morin, Andrew B. Sparks, Vladimír Kořínek et al. · Science · 1997 · 3.9K citations

Wnt signaling and cancer

Paul Polakis · Genes & Development · 2000 · 3.2K citations · Full text

Tumor Biology, Signaling Pathway, Gene Expression Profile +15

Somatic Frameshift Mutations in the <i>BAX</i> Gene in Colon Cancers of the Microsatellite Mutator Phenotype

Nicholas J. Rampino, Hiroyuki Yamamoto, Yurij Ionov et al. · Science · 1997 · 1.3K citations

Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3beta and beta -catenin and promotes GSK-3beta -dependent phosphorylation of beta -catenin

Satoshi Ikeda · The EMBO Journal · 1998 · 1.2K citations · Full text

Beta -Catenin, Signal Transduction, Negative Regulator +10