Automated classification between age-related macular degeneration and Diabetic macular edema in OCT image using image segmentation

Abstract

Age-related macular degeneration (AMD) and Diabetic macular edema (DME) are to lead causes to make a visual loss in people. People are suffered from the use of many time to diagnose and to wait for treatment both of diseases. This paper proposes a step of image segmentation to be divided the optical coherence tomography (OCT) to find the retinal pigment epithelium (RPE) layer and to detect a shape of drusen in RPE layer. Then, the RPE layer is used for finding retinal nerve fiber layer (RNFL) and for detecting a bubble of blood area in RNFL complex. Finally, this method uses a binary classification to classify two diseases characteristic between AMD and DME. We use 16 OCT images of a case study to segmentation and classify two diseases. In the experimental results, 10 images of AMD and 6 images of DME can be detected and classified to accuracy of 87.5%.