The <i>in vitro</i> dissolution of phenobarbitone sodium from ethyl cellulose microcapsules

Abstract

Abstract Microcapsules of sodium phenobarbitone, with a wall of ethyl cellulose, have been prepared. The size distribution was determined by use of standard sieves and the effect of core: wall ratio noted. Release of the drug into an aqueous medium was studied. The release pattern was found to have similar characteristics to the release of a drug from an insoluble porous matrix.