BMJ Case Reports · 2015 · 22 citations · 4 references
MedicineInfectious DiseasesNeurologyNeuro-ophthalmologyNeuroimmunologyNeuroinfectious DiseasesCranial Nerve InfectionsEncephalitisTrigeminal Nerve DisordersTrigeminal NeuralgiaViral Eye InfectionsViral InfectionsAntiviral TreatmentHerpesvirus ReactivationInfection Risk FactorsLong-term Neurologic SequelaeLong-term Neurological SequelaeTrigeminal Neuralgia Due To InfectionVaricella-zoster Virus InfectionsVaricella-zoster Virus Reactivation
Reactivation of varicella zoster virus (VZV) is not uncommon in older patients, particularly in cases of chronic autoimmune disorders and in patients taking immunosuppressant drugs. We present a case of a 57-year-old woman presenting with severe herpes zoster infection, involving the maxillary and ophthalmic branches of the trigeminal nerve. Despite an initial delay in instigating crucial antiviral treatment, the patient achieved an excellent recovery, with only some mild scarring at 2 months postinfection. Trigeminal herpes zoster is a potentially devastating clinical occurrence, and is associated with severe long-term neurological sequelae, including encephalitis, vision loss and postherpetic neuralgia. Physicians must be aware of risk factors and treatment modalities.
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Antonio Luigi Pastore, Giovanni Palleschi, Andrea Ripoli et al. · Journal of Medical Case Reports · 2013 · 79 citations · Full text