Abnormal accumulation and toxicity of polyamines in a difluoromethylornithine-resistant HTC cell variant

Polyamine metabolism and its importance in neoplastic growth and a target for chemotherapy.

Anthony E. Pegg · PubMed · 1988 · 1.5K citations

Chemoprevention Strategy, Pathology, Pharmaceutical Chemistry +18

Intracellular putrescine and spermidine deprivation induces increased uptake of the natural polyamines and methylglyoxal bis(guanylhydrazone)

Leena Alhonen‐Hongisto, Pauli Seppänen, Juhani Jänne · Biochemical Journal · 1980 · 182 citations · Full text

Spermatogenesis, Transport System, Culture Medium +16

Translational regulation of mammalian ornithine decarboxylase by polyamines.

Chaim Kahana, Daniel Nathans · Journal of Biological Chemistry · 1985 · 176 citations · Full text

Developmental Biology, Protein Expression, Biochemistry +13

Inhibition of Polyamine Metabolism: Biological Significance and Basis for New Therapies

Steven R. Meshnick · American Journal of Tropical Medicine and Hygiene · 1988 · 158 citations

Pharmacotherapy, Pharmaceutical Chemistry, Polyamine Biosynthesis +16

Determination of polyamines and related compounds by reversed-phase high-performance liquid chromatography: Improved separation systems

Nikolaus Seiler, B. Knödgen · Journal of Chromatography B Biomedical Sciences and Applications · 1985 · 139 citations

Solvent Extraction, Engineering, Separation Science +11