Differentiation of Plasmodium falciparum clones by means of a repetitive DNA probe

Supan Fucharoen, Nednapis Tirawanchai, Prapon Wilairat, Sakol Panyim, Sodsri Thaithong

Transactions of the Royal Society of Tropical Medicine and Hygiene · 1988 · 19 citations · 9 references

Concepts

Abstract

A recombinant DNA probe, pBRK1-14, was constructed by inserting a repetitive DNA fragment of 753 base pairs obtained from Plasmodium falciparum, isolate K1, into the EcoRI/PstI cloning sites of pBR322. This probe could discriminate between different parasite clones derived from a single isolate by hybridization with Southern genomic blots.

References

9