Familial benign frontotemporal deterioration with <i>C9ORF72</i> hexanucleotide expansion

Abstract

This family demonstrates that a benign evolution can be part of the growing spectrum of clinical phenotypes associated with neurodegenerative diseases caused by the C9ORF72 hexanucleotide expansion. Screening of this genetic marker should be considered in cases with this slow deterioration, especially if there is a family history.