Revelation on the potency of α₁-blockers – parallel blockade of angiotensin II receptor: A new finding

Abstract

Context: The problem of hypertension has gained enormous proportions in the past decade. Multifactorial etiology and complex pathophysiology of the disease has rendered the treatment of the disease a hard task. Sympathetic nervous system and the renin–angiotensin–aldosterone system are primary contributors of blood pressure homeostasis.