Green Synthesis of Pyrano[2,3‐<i>d</i>]‐pyrimidine Derivatives in Ionic Liquids

Abstract

Pyrano[2,3-d]pyrimidine derivatives were synthesized in high yields by a condensation reaction between arylmethylidenemalononitrile and barbituric acid using room-temperature ionic liquids such as 1- n -butyl-3-methylimidazolium tetrafluoroborate ([BMIm]BF4) or 1-butylpyridinium tetrafluoroborate ([BPy]BF4) as solvents under neutral conditions.