A Monovacant Lacunary Silicotungstate as an Efficient Heterogeneous Catalyst for Dehydration of Primary Amides to Nitriles

Abstract

Acting up with nitriles: A monovacant lacunary silicotungstate, TBA4[α-H4SiW11O39] (I) could act as an efficient heterogeneous catalyst for dehydration of primary amides. Various kinds of primary amides, including benzylic, double bond-containing, heteroaromatic, and aliphatic could be converted into the corresponding nitriles in moderate to excellent yields.