Ergebnisse der Verfahrensforschung, I. Synthese von <i>o</i>‐{(+)‐D‐2‐[4‐(4‐(Trifluormethyl)phenoxy)phenoxy]propionyl}‐aceton‐oxim

Abstract

Results of process Research I. Synthesis of O ‐{(+)‐D‐2‐[4‐(4‐(triluoromethyl)phenoxy)phenoxy]propionyl}‐acetone oxime Efficient and simple procedures for the preparation of O ‐{L‐[(sulfonyl)oxy]‐propionyl}‐oxime derivatives 7b‐e have been developed. The alleviation of 4‐[4‐(trifluoromethyl)phenoxy]phenol ( 11 ) with 7d , the final step of a technical synthesis of 1 , has been studied in detail.