Concepedia

Publication | Open Access

Role of secreted modular calcium-binding protein 1 (SMOC1) in transforming growth factor β signalling and angiogenesis

DOIFull Paper Access

78

Citations

45

References

2015

Year

Khader Awwad, Jiong Hu, Lei Shi, Nicole Mangels, Randa Abdel Malik, Nina Zippel, Beate Fißlthaler, Johannes A. Eble, Josef Pfeilschifter, Rüdiger Popp,
Cardiovascular Research

Abstract

These results indicate that SMOC1 is an ALK5 antagonist produced by endothelial cells that tips TGF-β signalling towards ALK1 activation, thus promoting endothelial cell proliferation and angiogenesis.

References

YearCitations

Page 1