Oral Self‐Administration of Et<scp>OH</scp>: Sex‐Dependent Modulation by Running Wheel Access in C57<scp>BL</scp>/6J Mice

Abstract

These data add to a burgeoning literature suggesting that the factors contributing to excessive alcohol use differ between males and females and that females may be especially sensitive to the influence of wheel manipulation. Elucidating the sex-dependent mechanisms mediating differences in alcohol sensitivity and response is critical to understanding the causes of alcoholism and in developing effective treatments and interventions.