Fish, meat, and risk of dementia: cohort study

TLDR

The PAQUID epidemiological study of cognitive and functional ageing provided the data for this research. During the third wave (1991‑92), investigators assessed meat and fish consumption frequency in 1,674 adults aged 68+ across 75 southwestern French parishes, followed them for up to seven years, and confirmed dementia diagnoses via neurologist evaluation.

Abstract

We obtained data from the PAQUID (Personnes Agees QUID) epidemiological study of cognitive and functional ageing (www.healthandage.net/html/min/paquid/entrance.htm). During the third wave of the study (1991-2) investigators visited 1674 people aged 68 and over without dementia and living at home in 75 parishes in southwestern France and recorded their frequency of consumption of meat and fish or seafood: daily, at least once a week (but not every day), from time to time (but not every week), never. Participants were followed up two, five, and seven years afterwards: 1416 (84.6 %) had at least one follow up visit. All the participants who had lost three points or more on the mini-mental state examination since a previous visit or were suspected of having dementia according to the criteria of the Diagnostic and Statistical Manual of Mental Disorders , third edition, revised (DSM-III-R) were visited by a neurologist to confirm the diagnosis. We …