Patterns of relapse of N2 nonsmall-cell lung carcinoma patients treated with preoperative chemotherapy

Abstract

The current study found that preoperative chemotherapy for cN2 decreases the risk of visceral metastasis but is associated with a high rate of isolated brain metastases. Prophylactic cranial irradiation may need to be reinvestigated in clinical trials, especially in patients who present with an adenocarcinoma.