In silico model of drug permeability across sublingual mucosa

Correlation between oral drug absorption in humans and apparent drug permeability coefficients in human intestinal epithelial (Caco-2) cells

Per Artursson, Johan Karlsson · Biochemical and Biophysical Research Communications · 1991 · 1.8K citations

Health Sciences, Medicine, Physiology +9

Predicting Skin Permeability

Russell O. Potts, Richard H. Guy · Pharmaceutical Research · 1992 · 1.5K citations

Rate-Limited Steps of Human Oral Absorption and QSAR Studies

Yuan H. Zhao, Michael H. Abraham, Joelle Le et al. · Pharmaceutical Research · 2002 · 699 citations

Development of a new physicochemical model for brain penetration and its application to the design of centrally acting H2 receptor histamine antagonists

Rodney C. Young, Robert Cameron Mitchell, Thomas H. Brown et al. · Journal of Medicinal Chemistry · 1988 · 517 citations

Brain Penetration, Rational Approach, Anesthetic Mechanism +19

Correlation of Human Jejunal Permeability (in Vivo) of Drugs with Experimentally and Theoretically Derived Parameters. A Multivariate Data Analysis Approach

Susanne Winiwarter, Nicholas M. Bonham, Fredrik Ax et al. · Journal of Medicinal Chemistry · 1998 · 446 citations

Pharmaceutical Science, Gastroenterology, Effective Permeability +18