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Quercitrin: An Antileishmanial Flavonoid Glycoside from<i>Kalanchoe pinnata</i>
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2006
Year
Medicinal ChemistryFlavonoid GlycosideBioorganic ChemistryAntileishmanial ActivityBiochemistryAntiparasitic AgentMedicineNatural SciencesGlycobiologyPotent Antileishmanial CompoundPhytopharmacologyPhytochemicalAntileishmanial Flavonoid GlycosidePhytochemistryPharmacologyDrug Discovery
Quercitrin (quercetin 3- O-alpha- L-rhamnopyranoside), one of the constituents of the biologically active aqueous extract obtained from Kalanchoe pinnata, is demonstrated to be a potent antileishmanial compound (IC50 approximately 1 microg/mL) with a low toxicity profile. This is the first time that antileishmanial activity is demonstrated for a flavonoid glycoside.