Synthetic study toward myrocin analogues. Highly enantio- and diastereo-selective synthesis of a tetracyclic ring system

Abstract

An intramolecular Diels–Alder reaction for the construction of a lactone ring fused-tricyclic ring system has been developed using propionate as the dienophile. As an application of this reaction, an enantio- and diastereo-selective synthesis of a tetracyclic ring system of a myrocin analogue has been studied.