Publication | Closed Access
Catalysis‐Based Total Synthesis of Latrunculin B
171
Citations
45
References
2003
Year
EngineeringProtein AssemblyMolecular BiologyChemistryFlexible ApproachChemical BiologyProtein FoldingBioorganometallic ChemistryMolecular RecognitionMulti-protein AssemblySelective Actin-binding LatrunculinsBiochemistryTotal SynthesisBiomolecular InteractionCatalysisProbe MoleculesSynthesis MethodNatural SciencesSynthetic Chemistry
The highly selective actin-binding latrunculins (e.g. 1) play a prominent role as probe molecules in chemical biology. A highly concise, productive, and inherently flexible approach to 1 illustrates the excellent profile and use of metal-catalyzed CC bond formations.
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