Targeting Ligand-Induced Binding Sites on GPIIb/IIIa via Single-Chain Antibody Allows Effective Anticoagulation Without Bleeding Time Prolongation - Concepedia

Concepedia

Publication | Open Access

Targeting Ligand-Induced Binding Sites on GPIIb/IIIa via Single-Chain Antibody Allows Effective Anticoagulation Without Bleeding Time Prolongation

DOI Full Paper Access

82

Citations

35

References

2007

Year

Patrick Stoll, Nicole Bassler, Christoph E. Hagemeyer, Steffen U. Eisenhardt, Yung‐Chih Chen, René Schmidt, Meike Schwarz, Ingo Ahrens, Yasuhiro Katagiri, Benedikt H. J. Pannen,

Arteriosclerosis Thrombosis and Vascular Biology

Abstract

The novel clot-targeting approach of anticoagulants via single-chain antibody directed against a LIBS-epitope on GPIIb/IIIa promises effective anticoagulation with reduced bleeding risk.

References

	Year	Citations

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