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Steroid Hormone Receptors in Pelvic Muscles and Ligaments in Women
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1990
Year
Hormonal ContraceptiveGynecologySteroid Hormone ReceptorsOvarian CancerUrogynecologyWomen's PhysiologyPublic HealthMyometrial ContractilitySteroid MetabolismMonoclonal AntibodyInfertilityEstrogen TreatmentHormonal ReceptorEndocrinologyOvarian HormoneUrologyProgesterone ReceptorsUterine ReceptivityWomen's HealthMedicineReproductive Hormone
Using monoclonal antibody assay techniques estrogen receptors (ER) and progesterone receptors (PgR) were quantitated in female pelvic floor muscles, urogenital ligaments and uterus (myometrium). Receptors were detected in all these structures. In addition qualitative assessment showed distinct nuclear staining in the same structures. ER and PgR were not found in the musculus rectus abdominis with either method. The findings provide a rationale for estrogen treatment in women with urogenital disorders.