The spread of plasmids as a function of bacterial adaptability
FEMS Microbiology Ecology · 1994 · 78 citations · 13 references
BacteriologyAntibiotic ResistanceBacterial PathogensDrug ResistanceHorizontal SpreadEvolutionary MicrobiologyAntimicrobial ResistanceMolecular MicrobiologyClinical MicrobiologyBiologyAntimicrobial Resistance GeneNatural SciencesEvolutionary BiologyBacterial AdaptabilityMicrobiologyNatural Bacterial PopulationsMedicineSat GenesMicrobial Genetics
The horizontal spread of plasmids among natural bacterial populations serves as an evolutionary function for adaptation to the ups and downs in nature. Recent evolutionary challenges are the introduction of antibiotics and the creation of new environmental conditions in agriculture and medical care. As a consequence, surviving bacterial populations have acquired new genetic determinants which enable the colonisation and maintenance in distinct ecological niches. The acquisition of new genetic determinants can take place rather rapidly because of the plasmids' biology: their self-transferability and their ability to pick up genes. As an example of horizontal gene transfer, from an ecological and evolutionary viewpoint, the emergence of resistance to streptothricins (sat genes) is described.
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THE EVOLUTIONARY ADVANTAGE OF RECOMBINATION
Joseph Felsenstein · Genetics · 1974
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Martine Couturier, F Bex, P L Bergquist et al. · Microbiological Reviews · 1988
Pathogenic MicrobiologyBacteriologyPathogen Characterization+3
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