Induction of tumor suppression and glandular differentiation of A549 lung carcinoma cells by dominant-negative IGF-I receptor

Antiapoptotic Signalling by the Insulin-Like Growth Factor I Receptor, Phosphatidylinositol 3-Kinase, and Akt

George Kulik, Anke Klippel, Michael J. Weber · Molecular and Cellular Biology · 1997 · 1.1K citations · Full text

Life Sciences, Cell Biology, Apoptosis +16

Epidermal growth factor induces rapid, reversible aggregation of the purified epidermal growth factor receptor

Yosef Yarden, Joseph Schlessinger · Biochemistry · 1987 · 628 citations

Life Sciences, Biochemistry, Molecular Biology +9

Effect of a null mutation of the insulin-like growth factor I receptor gene on growth and transformation of mouse embryo fibroblasts.

Christian Sell, Guillaume Duménil, Catherine Deveaud et al. · Molecular and Cellular Biology · 1994 · 523 citations · Full text

Life Sciences, Genetics, Molecular Biology +15

Overexpression of the human insulinlike growth factor I receptor promotes ligand-dependent neoplastic transformation.

Michael Kaleko, William J. Rutter, A. Dusty Miller · Molecular and Cellular Biology · 1990 · 399 citations · Full text

Medicine, Cell Biology, Oncology +17

The insulin-like growth factor I receptor protects tumor cells from apoptosis in vivo.

Mariana Resnicoff, David Abraham, Wiboonchai Yutanawiboonchai et al. · PubMed · 1995 · 386 citations

Life Sciences, Cancer Biology, Oncology +17