Cornea · 2004 · 14 citations · 15 references
MedicineDermatologyOphthalmologyAllergyHypersensitivityOcular PathologyAtopic DermatitisCorneal DisordersCorneal PathologyCorneal UlcerationCorneal Wound HealingAllergic KeratoconjunctivitisAmniotic Membrane TherapyCorneal EpithelializationNonhealing Corneal UlcersWound Epithelialization
PURPOSE: To present a case of allergic corneal ulcer in a patient with atopic keratoconjunctivitis (AKC) that was persistent for 6 months and healed by amniotic membrane patching. CASE REPORT: A 27-year-old male patient with a corneal ulcer associated with AKC persistent for 6 months despite conventional treatment underwent amniotic membrane patching. On removal of the amniotic membrane patch after 1 week, the corneal ulcer that had been persistent for 6 months had healed completely. CONCLUSION: We experienced a case with corneal ulcer that was persistent for 6 months and healed dramatically within 1 week with improved vision and corneal clarity. In such severe and persistent cases requiring rapid epithelialization, amniotic membrane should be considered as an adjunct to conventional therapy.
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Growth factor mRNA and protein in preserved human amniotic membrane
Noriko Koizumi, Tsutomu Inatomi, Chie Sotozono et al. · Current Eye Research · 2000 · 629 citations
Antiinflammatory Effects of Amniotic Membrane Transplantation in Ocular Surface Disorders
Shigeto Shimmura, Jun Shimazaki, Yoshie Ohashi et al. · Cornea · 2001 · 375 citations
Medicine, Immunology, Ophthalmology +12