The 3260 mutation in mitochondrial DNA can cause mitochondrial myopathy, encephalopathy, lactic acidosis, and strokelike episodes (MELAS)

Sequence and organization of the human mitochondrial genome

Stephen K. Anderson, Alan T. Bankier, B. G. Barrell et al. · Nature · 1981 · 9.7K citations

Medicine, Genetics, Molecular Genetics +12

A mutation in the tRNALeu(UUR) gene associated with the MELAS subgroup of mitochondrial encephalomyopathies

Yu‐ichi Goto, Ikuya Nonaka, Satoshi Horai · Nature · 1990 · 2.1K citations

Life Sciences, Genetics, Molecular Genetics +11

Maternally inherited myopathy and cardiomyopathy: association with mutation in mitochondrial DNA tRNALeu(UUR)

Massimo Zeviani, Cinzia Gellera, Carlo Antozzi et al. · The Lancet · 1991 · 383 citations

Medicine, Genetics, Molecular Genetics +12

A new mtDNA mutation associated with mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS)

Yu‐ichi Goto, Ikuya Nonaka, Satoshi Horai · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · 1991 · 327 citations

Life Sciences, Genetics, Molecular Genetics +17

Strongly succinate dehydrogenase–reactive blood vessels in muscles from patients with mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke‐like episodes

Hitomi Hasegawa, Taro Matsuoka, Yu‐ichi Goto et al. · Annals of Neurology · 1991 · 182 citations

Life Sciences, Pathobiology, Pathology +17