Hepatoprotective activity of<i>Glycosmis pentaphylla</i>against paracetamol-induced hepatotoxicity in Swiss albino mice

Abstract

These biochemical observations were supplemented by histopathological examination of liver sections from different experimental groups and corroborated the hepatoprotective efficacy of methanol and petroleum ether plant extract. The methanol extract (400 mg/kg) of G. pentaphylla is able to alter the toxic condition of the hepatocytes so as to protect the membrane integrity against paracetamol-induced leakage of marker enzymes.