High Rates of Mortality and Morbidity Occur in Infants With Parenteral Nutrition–Associated Cholestasis

Abstract

Infants with PN-associated cholestasis have high rates of mortality despite the presence of some gastrointestinal function. These data support further evaluation and the development of novel forms of therapy for babies with parenteral-associated CB > or =2 mg/dL with emphasis on interventions for infants with a CB >10 mg/dL.