Titanocene derivatives of purine and adenine. Synthesis and characterization of reaction products with (η⁵-C₅H₅)₂Ti(CO)₂, (η⁵-C₅H₅)₂TiCl, and (η⁵-C₅H₅)₂TiCl₂

Abstract

The reaction of CpTi(CO) 2 (1), Cp 2 TiCl (2), and Cp 2 TiCl 2 (3) (Cp = η 5 -C 5 H 5 ) with purine (PuH) and adenine (AdH) in organic solvents is described. The compound 1 reacts with both molecules in an oxidative fashion giving Cp 2 Ti(C 5 H 3 N 4 )(C 5 H 4 N 4 ) (4) and (Cp 2 Ti) 2 (C 5 H 3 N 5 ) (5) with concomitant liberation of molecular carbon monoxide and hydrogen (4:1) following a first order rate law in metal complex. The compound 2 forms an adduct compound Cp 2 TiCl(C 5 H 4 N 4 ) (6) with PuH. Monosubstituted derivatives Cp 2 TiCl(C 5 H 3 N 4 ) (7) and Cp 2 TiCl(C 5 H 4 N 5 ) (8) are formed from the reaction of the deprotonated bases with 3. In addition to the usual elemental analysis, the characteristic ir, 1 H nmr, epr, and ms results are given for the new compounds.