The serum-free light chain assay cannot replace 24-hour urine protein estimation in patients with plasma cell dyscrasias

Abstract

The serum-free light chain (SFLC) assay provides useful information in patients with plasma cell dyscrasias who secrete no or small quantities of monoclonal protein.[1][1],[2][2] Changes in SFLC over a period of time correlate with changes in the amounts of 24-hour urinary monoclonal protein.[3][3]