Publication | Closed Access
The Role of β‐Glucuronidase in Induction of Apoptosis by Genistein Combined Polysaccharide (GCP) in Xenogeneic Mice Bearing Human Mammary Cancer Cells
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Citations
2
References
2003
Year
Beta-glucuronidase ActivityApoptosisImmunologyGlycobiologyCell DeathCell ProliferationCancer BiologyTumor BiologyOxidative StressCancer Cell BiologyTumor ProliferationAnti-cancer AgentCancer ResearchGlycosylationGenistein Combined PolysaccharideCell BiologyTumor MicroenvironmentEndocrine-related CancerNude MiceBreast CancerMedicineCancer Growth
In order to reveal the mechanisms underlying genistein combined polysaccharide (GCP) inhibition of tumor proliferation, we investigated the effects of GCP on the growth of human breast cancer cells transplanted to athymic nude mice. We further investigated the metabolism of genistein and its association with the beta-glucuronidase activity in tumor and normal tissues.
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