Suicidal inactivation of microsomal cytochrome P-450 by halothane under hypoxic conditions

The Carbon Monoxide-binding Pigment of Liver Microsomes

Tsuneo Omura, Ryo Sato · Journal of Biological Chemistry · 1964 · 11.8K citations · Full text

Hepatology, Biochemistry, Carbon Monoxide-binding Pigment +9

The metabolism of methylated aminoazo dyes. V. Evidence for induction of enzyme synthesis in the rat by 3-methylcholanthrene.

Allan H. Conney, E. C. Miller, J. A. Miller · PubMed · 1956 · 395 citations

Bioorganic Chemistry, Organic Chemistry, Toxicological Mechanism +17

The mechanism of reductive dehalogenation of halothane by liver cytochrome P450

H J Ahr, Laurence J. King, Wolfgang Nastainczyk et al. · Biochemical Pharmacology · 1982 · 135 citations

Halogenation, Biochemistry, Medicine +12

Halothane Hepatitis

FRANCOISE M. T. CARNEY, Russell A. Van Dyke · Anesthesia & Analgesia · 1972 · 111 citations

The Solubility of Halothae in Blood and Tissue Homogeates

C. Philip Larson, Edmond I. Eger, J. W. Severinghous · Anesthesiology · 1962 · 109 citations

Halogenation, Tissue Homogeates, Clinical Chemistry +1