Concepedia

Enhancement of RAD51 recombinase activity by the tumor suppressor PALB2

Eloïse Dray, Julia Etchin, Claudia Wiese, Dorina Saro, Gareth J. Williams, Michal Hammel, Xiong Yu, Vitold E. Galkin, Dongqing Liu, Miaw-Sheue Tsai,

Nature Structural & Molecular Biology · 2010 · 175 citations · 27 references

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27

BRCA2 Is Required for Homology-Directed Repair of Chromosomal Breaks

Mary Ellen Moynahan, Andrew J. Pierce, Maria Jasin · Molecular Cell · 2001 · 1K citations · Full text

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PALB2, which encodes a BRCA2-interacting protein, is a breast cancer susceptibility gene

Nazneen Rahman, Sheila Seal, Deborah J. Thompson et al. · Nature Genetics · 2006 · 992 citations · Full text

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Control of BRCA2 Cellular and Clinical Functions by a Nuclear Partner, PALB2

Bing Xia, Qing Sheng, Koji Nakanishi et al. · Molecular Cell · 2006 · 862 citations · Full text

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Biallelic mutations in PALB2 cause Fanconi anemia subtype FA-N and predispose to childhood cancer

Sarah Reid, Detlev Schindler, Helmut Hanenberg et al. · Nature Genetics · 2006 · 643 citations

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PALB2 is an integral component of the BRCA complex required for homologous recombination repair

Shirley M.-H. Sy, Michael S.Y. Huen, Junjie Chen · Proceedings of the National Academy of Sciences · 2009 · 609 citations · Full text

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