Concepedia

Primary Testicular Dysfunction Is a Major Contributor to Abnormal Pubertal Development in Males with Prader-Willi Syndrome

Harry J. Hirsch, Talia Eldar‐Geva, Fortu Benarroch, Orit Rubinstein, Varda Gross‐Tsur

The Journal of Clinical Endocrinology & Metabolism · 2009 · 73 citations · 30 references

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Abstract

Pubertal development in PWS is characterized by normal adrenarche, variable hypothalamic dysfunction, and hypogonadism due to a unique testicular defect. Primary testicular dysfunction is a major component of hypogonadism in PWS.

References

30

Prader–Willi syndrome

Suzanne B. Cassidy, Daniel J. Driscoll · European Journal of Human Genetics · 2008 · 587 citations · Full text

Recommendations for the Diagnosis and Management of Prader-Willi Syndrome

Anthony P. Goldstone, Anthony Holland, B. P. Hauffa et al. · The Journal of Clinical Endocrinology & Metabolism · 2008 · 512 citations · Full text

Mullerian inhibiting substance in humans: normal levels from infancy to adulthood.

Mary Lee, Patricia K. Donahoe, Tomonobu Hasegawa et al. · The Journal of Clinical Endocrinology & Metabolism · 1996 · 410 citations · Full text

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Normal Growth and Variation in the Male Genitalia from Birth to Maturity

WILLIAM A. SCHONFELD, Gilbert W. Beebe · The Journal of Urology · 1942 · 318 citations

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Secondary sexual characteristics in boys: estimates from the national health and nutrition examination survey III, 1988-1994.

Marcia E. Herman‐Giddens, Lily Wang, Gary G. Koch · PubMed · 2001 · 314 citations