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2-(Substituted phenyl)oxazolo[4,5-b]pyridines and 2-(substituted phenyl)oxazolo[5,4-b]pyridines as nonacidic antiinflammatory agents
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1978
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Medicinal ChemistryAnti-inflammatoryPharmacological StudyMedicineGood AntiinflammatoryPharmacological AgentOrganic ChemistryPharmacotherapyAnalgesic ActivityHeterocycle ChemistryPharmacologyPharmaceutical ChemistryDrug DiscoverySubstituted Phenyl
Some 2-(substituted phenyl)oxazolo[4,5-b]pyridines and 2-(substituted phenyl)oxazolo[5,4-b]pyridines have good antiinflammatory and analgesic activity. A few possess activity comparable to phenylbutazone or indomethacin without producing the irritation in the gastrointestinal tract that acidic antiinflammatory compounds cause.