Growth Differentiation Factor 15, ST2, High-Sensitivity Troponin T, and N-Terminal Pro Brain Natriuretic Peptide in Heart Failure with Preserved vs. Reduced Ejection Fraction

Abstract

Our study provides comparative data on physiologically distinct circulating biomarkers in HFPEF, HFREF, and controls from the same community. These data suggest a prominent role for myocardial injury (hsTnT) with increased wall stress (NT-proBNP) in HFREF, and systemic inflammation (GDF15) in HFPEF.