Concepedia

Correlation of integrin β3 mRNA and vascular endothelial growth factor protein expression profiles with the clinicopathological features and prognosis of gastric carcinoma

Shuguang Li, Zai‐yuan Ye, Zhong‐Sheng Zhao, Hou‐Quan Tao, Yuanyu Wang, Chun‐Yu Niu

World Journal of Gastroenterology · 2008 · 25 citations · 19 references

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Abstract

Integrin beta3 and VEGF expression can synergistically enhance tumor angiogenesis, and may play a crucial role in invasion and metastasis of gastric carcinoma. Therefore, they may be prognostic biomarkers and novel molecular therapeutic targets.

References

19

Integrin Structure

Martin J. Humphries · Biochemical Society Transactions · 2000 · 385 citations

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Mechanisms of Integrin–Vascular Endothelial Growth Factor Receptor Cross-Activation in Angiogenesis

Ganapati H. Mahabeleshwar, Weiyi Feng, Kumar B. Reddy et al. · Circulation Research · 2007 · 294 citations · Full text

, , +16

Vascular Endothelial Growth Factor Receptor 3 Is Involved in Tumor Angiogenesis and Growth

Pirjo Laakkonen, Marika Waltari, Tanja Holopainen et al. · Cancer Research · 2007 · 241 citations

Complementary Roles for Receptor Clustering and Conformational Change in the Adhesive and Signaling Functions of Integrin αIIbβ3

Takaaki Hato, Nisar A. Pampori, Sanford J. Shattil · The Journal of Cell Biology · 1998 · 234 citations · Full text

, , +20

Expression and activation of α<sub>v</sub>β<sub>3</sub> integrins by SDF‐1/CXC12 increases the aggressiveness of prostate cancer cells

Yan‐Xi Sun, Ming Fang, Jianhua Wang et al. · The Prostate · 2006 · 171 citations