Interactions between vascular actions of detergent and catecholamines in perfused gills of European eel, <i>Anguilla anguilla</i> L. and brown trout, <i>Salmo trutta</i> L.

Abstract

Noradrenaline induced vasodilation in isolated perfused eel or trout gills was inhibited by propranolol, aβ‐adrenergic blocking agent. The noradrenaline effect was much reduced in gills of fish which had been kept in 1 mg/l solutions of the detergent LAS (linear alkylate sulphonate; 12C chain length). LAS produced concentration‐dependent vasodilation, which was inhibited by propranolol, in eel and trout gills. Noradrenaline produced additional vasodilation in eel and trout gills which had been dilated by 2.10 −8 m LAS but had no effect on trout gills perfused with 2.10 −7 m LAS. Gills from trout which had been kept in 0.1 mg l ‐1 LAS responded to noradrenaline normally but the propranolol inhibition appeared to be potentiated.