Concepedia

Plagiochin E, a botanic-derived phenolic compound, reverses fungal resistance to fluconazole relating to the efflux pump

Xiaohan Guo, Ping Leng, Yilei Yang, Lu‐Gang Yu, Hong‐Xiang Lou

Journal of Applied Microbiology · 2008 · 61 citations · 18 references

DOI

Abstract

These results indicate that the combination of PLE and FLC may provide an approach for the clinical therapy of fungus infection induced by FLC-resistant strains.

References

18

Mechanisms of resistance to azole antifungal agents in Candida albicans isolates from AIDS patients involve specific multidrug transporters

Dominique Sanglard, Karl Kuchler, Françoise Ischer et al. · Antimicrobial Agents and Chemotherapy · 1995 · 814 citations · Full text

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Cloning of Candida albicans genes conferring resistance to azole antifungal agents: characterization of CDR2, a new multidrug ABC transporter gene

Dominique Sanglard, Françoise Ischer, Michel Monod et al. · Microbiology · 1997 · 584 citations

Multiple efflux mechanisms are involved in Candida albicans fluconazole resistance

G D Albertson, Masakazu Niimi, Richard D. Cannon et al. · Antimicrobial Agents and Chemotherapy · 1996 · 263 citations · Full text

, , +13

Multiple Resistance Mechanisms among <i>Aspergillus fumigatus</i> Mutants with High-Level Resistance to Itraconazole

A. M. do Nascimento, Gustavo H. Goldman, Steven Park et al. · Antimicrobial Agents and Chemotherapy · 2003 · 255 citations · Full text

, , +18

Synergistic Antifungal Activities of Bafilomycin A <sub>1</sub> , Fluconazole, and the Pneumocandin MK-0991/Caspofungin Acetate (L-743,873) with Calcineurin Inhibitors FK506 and L-685,818 against <i>Cryptococcus neoformans</i>

Maurizio Del Poeta, Maria Cristina Cruz, María E. Cárdenas et al. · Antimicrobial Agents and Chemotherapy · 2000 · 172 citations · Full text

, , +21