Evaluation of a biodegradable ceramic

TLDR

The study evaluated porous tricalcium phosphate, a biodegradable ceramic. In vivo, the ceramic rapidly infiltrated cancellous and cortical bone, was slowly resorbed, elicited no adverse tissue or systemic reactions, and was deemed safe for clinical use as a bone graft substitute.

Abstract

An evaluation of a porous biodegradable ceramic, tricalcium phosphate, has been carried out. When implanted in cancellous bone, it is rapidly infiltrated with bone and slowly resorbed. When held rigidly against raw, bleeding, cortical bone, again rapid bone ingrowth occurs. The material does not give rise to any untoward tissue reaction, nor does it cause any systemic reaction. It can therefore be concluded that the material is safe for use in clinical practice, and can be used in specific instances either to replace or to supplement bone grafting.