Comparison of Outcomes after Delayed Graft Function: Sirolimus-Based Versus Other Calcineurin-Inhibitor Sparing Induction Immunosuppression Regimens

Abstract

In our analysis of a large and modern cohort of adult cadaveric transplant recipients with DGF, induction immunosuppression with a depleting antibody preparation reduced rejection, whereas SRL prolonged DGF duration. All three CNI-sparing induction IS regimens resulted in comparable patient survival, graft survival, and graft function.