New antiepileptic agents: strategies for drug development

Anticonvulsant activity of (+)‐5‐methyl‐10, 11‐dihydro‐5H‐dibenzo[a, d]cyclohepten‐5, 10‐imine (MK‐801), a substance with potent anticonvulsant, central sympathomimetic, and apparent anxiolytic properties

Bradley V. Clineschmidt, Gregory E. Martin, Patricia R. Bunting · Drug Development Research · 1982 · 498 citations

Medicine, Neurology, Pharmacology +12

Antiepileptic Drug Development Program

Roger J. Porter, James J. Cereghino, G. D. Gladding et al. · Cleveland Clinic Journal of Medicine · 1984 · 492 citations

Medicine, Pharmacology, Pharmacotherapy +13

Anticonvulsant and antiepileptogenic actions of MK-801 in the kindling and electroshock models

James O McNamara · Neuropharmacology · 1988 · 312 citations

Medicine, Neuroscience, Pharmacology +9

A NEW SERIES OF ANTICONVULSANT DRUGS TESTED BY EXPERIMENTS ON ANIMALS

H. Houston Merritt · Archives of Neurology And Psychiatry · 1938 · 236 citations

Medicine, Medicinal Chemistry, Pharmacology +12

Development of New Pharmacological Agents for Epilepsy: Lessons from the Kindling Model

James O McNamara · Epilepsia · 1989 · 68 citations

Medicine, Neuroscience, Pharmacology +10