High prevalence of <i>BRAF</i> mutation in a Brazilian cohort of patients with sporadic papillary thyroid carcinomas

Abstract

These findings provide further evidence that BRAF might be associated with a more aggressive phenotype and less differentiated state due to decreased expression of iodide-metabolizing genes. The search for a BRAF mutation in the current study population appears to be valuable for predicting prognosis and guiding management in patients with PTC.