ALLOANTIBODY- AND T CELL-MEDIATED IMMUNITY IN THE PATHOGENESIS OF TRANSPLANT ARTERIOSCLEROSIS

Abstract

Taken together, these findings indicate that endothelialitis is antibody-independent, whereas antibodies potentiate and can be sufficient for fully developed, fibrous, chronic allograft vasculopathy. Therapeutic strategies for controlling chronic lesions must consider inhibition of the humoral response.