Medical Physics · 1997 · 74 citations · 14 references
MedicineNuclear MedicineRadiologyRadiation DosimetryRadiation TransportRadiobiologyEquivalent DoseIn Vivo DosimetryRadiation TherapyRadiobiological ConsiderationsStent PlacementCalculation MethodologyDepth Dose DistributionDose Distribution CalculationsIon Implantation EffectsIon Implantation SimulationRadiation Damage In Vascular TissueRadiation Dose EstimationRadiographic Film Dosimetry
The near field dose distribution of a realistic vascular stent impregnated with radioactive 32P is calculated employing the dose-point-kernel (DPK) method in a homogeneous and uniform medium. The cylindrical wire mesh geometry for the Palmaz-Schatz [Palmaz-Schatz is a tradename of Cordis (a Johnson & Johnson company)] stent is incorporated in the model calculation, and the dose distribution generated by the beta particles emitted from the decayed radioactive 32P is computed at distances ranging from 0.1 to 2 mm exterior to the stent surface. Dose measurements were obtained using radiochromic film dosimetry media on an actual Palmaz-Schatz half-stent impregnated with 32P using ion implantation, and compared to the DPK model predictions. The close agreement between the model calculation and the film dosimetry data confirms the validity of the model which can be adapted to a variety of different stent designs.
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Patrick W. Serruys, Peter de Jaegere, Ferdinand Kiemeneij et al. · New England Journal of Medicine · 1994 · 4.5K citations · Full text
Philip James Muench, Ali S. Meigooni, Ravinder Nath et al. · Medical Physics · 1991 · 198 citations
Inhibition of Neointimal Proliferation With Low-Dose Irradiation From a β-Particle–Emitting Stent
John R. Laird, Andrew J. Carter, William M. Kufs et al. · Circulation · 1996 · 155 citations
Medicine, Cardiology, Surgery +16