The P2X₇ receptor–inflammasome complex has a role in modulating the inflammatory response in primary <scp>S</scp>jögren's syndrome

Abstract

The results of this study suggest an involvement of the P2X7 R-inflammasome-caspase-1-IL-18 axis in the development of pSS exocrinopathy. This finding provides the basis for studying the complex mechanisms underlying pSS, as well as for developing novel potential therapeutic strategies.