Concepedia

Evaluation of the immortalised mouse brain capillary endothelial cell line, b.End3, as an in vitro blood–brain barrier model for drug uptake and transport studies

Yadollah Omidi, Lee Ann Campbell, Jaleh Barar, David J. Connell, Saeed Akhtar, Mark Gumbleton

Brain Research · 2003 · 249 citations · 61 references

DOI

Concepts

References

61

Absence of the mdr1a P-Glycoprotein in mice affects tissue distribution and pharmacokinetics of dexamethasone, digoxin, and cyclosporin A.

Alfred H. Schinkel, Els Wagenaar, Liesbeth van Deemter et al. · Journal of Clinical Investigation · 1995 · 1.1K citations · Full text

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Expression Cloning and Characterization of a Transporter for Large Neutral Amino Acids Activated by the Heavy Chain of 4F2 Antigen (CD98)

Yoshikatsu Kanai, Hiroko Segawa, Ken‐ichi Miyamoto et al. · Journal of Biological Chemistry · 1998 · 1.1K citations · Full text

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P-Glycoprotein, a gatekeeper in the blood–brain barrier

Alfred H. Schinkel · Advanced Drug Delivery Reviews · 1999 · 954 citations

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A cell culture model of the blood-brain barrier.

Lee L. Rubin, Deborah E. Hall, Stephen Porter et al. · The Journal of Cell Biology · 1991 · 774 citations · Full text

, , +17

Human L-type amino acid transporter 1 (LAT1): characterization of function and expression in tumor cell lines

Osamu Yanagida, Yoshikatsu Kanai, Arthit Chairoungdua et al. · Biochimica et Biophysica Acta (BBA) - Biomembranes · 2001 · 739 citations

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