Capturing Amplitude Changes of Low-Frequency Fluctuations in Functional Magnetic Resonance Imaging Signal: A Pilot Acupuncture Study on <i>NeiGuan</i> (PC6)

Abstract

These findings imply that stimulating PC6 can change the amplitude of the intrinsic cortical activity of the brain. In particular, a continuous and temporally consistent effect of acupuncture within PCC not the common brain circuit of pain including ACC and cerebellum was observed. Considering the cognitive functions and deficits of the relevant areas in mild cognitive impairment and Alzheimer disease, acupuncture on PC6 could potentially affect both psychiatric and neurological disorders. Thus, stimulating PC6 may be a candidate method for improving cognitive impairment.