Inhibition of enkepha,in metabolism by, and antinociceptive activity of, bestatin, an aminopeptidase inhibitor

SYNTHETIC ANALGESICS. II. DITHIENYLBUTENYL- AND DITHIENYLBUTYLAMINES

Nathan B. Eddy, Dorothy G. Leimbach · Journal of Pharmacology and Experimental Therapeutics · 1953 · 1.8K citations

Nursing, Medicinal Chemistry, Pharmacology +13

PHARMACOLOGICAL EFFECTS PRODUCED BY INTRACEREBRAL INJECTION OF DRUGS IN THE CONSCIOUS MOUSE

Thomas J. Haley, WF McCormick · British Journal of Pharmacology and Chemotherapy · 1957 · 1.5K citations · Full text

Medicine, Neuroscience, Pharmacology +12

Bestatin, an inhibitor of aminopeptidase B, produced by actinomycetes.

HAMAO UMEZAWA, TAKAAKI AOYAGI, Suda Hiroyuki et al. · The Journal of Antibiotics · 1976 · 721 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +7

The enkephalinase inhibitor thiorphan shows antinociceptive activity in mice

B P Roques, M C Fournié-Zaluski, E. Soroca et al. · Nature · 1980 · 707 citations

Medicine, Neuroscience, Pharmacology +10

High-affinity enkephalin-degrading peptidase in brain is increased after morphine

Bernard Malfroy, Jean-Paul Swerts, Anne Guyon et al. · Nature · 1978 · 650 citations

Medicine, Neuroscience, Pharmacology +12