Survival After Pancreaticoduodenectomy is not Improved by Extending Resections to Achieve Negative Margins

Abstract

Survival after pancreaticoduodenectomy is not improved by extending pancreatic resections to achieve negative margins after initially positive intraoperative frozen sections. Tumor-specific factors beyond the presence of disease at a surgical margin are responsible for the abbreviated survival seen in patients undergoing R1 resections.