Stereoscpecific actions of morphine on single neurones in the brain stem of the rat

Identification of two related pentapeptides from the brain with potent opiate agonist activity

Joel W. Hughes, Terry Smith, H. W. Kosterlitz et al. · Nature · 1975 · 3.8K citations

Medicine, Medicinal Chemistry, Pharmacology +13

Opiate Receptor: Demonstration in Nervous Tissue

Candace B. Pert, Solomon H. Snyder · Science · 1973 · 2.4K citations

Medicine, Neuroscience, Pharmacology +10

Isolation of an endogenous compound from the brain with pharmacological properties similar to morphine

John Hughes · Brain Research · 1975 · 981 citations

Medicine, Neuroscience, Pharmacology +14

Regional Distribution of Opiate Receptor Binding in Monkey and Human Brain

Michael J. Kuhar, Candace B. Pert, Solomon H. Snyder · Nature · 1973 · 818 citations

Medicine, Neurobiology, Neuroscience +9

Stereospecific and Nonspecific Interactions of the Morphine Congener Levorphanol in Subcellular Fractions of Mouse Brain

Avram Goldstein, Louise I. Lowney, B K Pal · Proceedings of the National Academy of Sciences · 1971 · 413 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +13